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Photobiomodulation (PBM) for Alopecia Androgenetic alopecia (AGA) The results of PBM for AGA suggest that the fraction of all the hair follicle (HF) in the anagen phase isincreased. This may be due to the ability of PBM to stimulate the mitochondria in the bulge stem cells. Stem cells are quiescent cells that have adapted to survive in their hypoxic niche. One of the mostdamaging agents to the longevity of cells is oxidative damage to DNA and other biomolecules, caused by the ROS that are an inevitable by-product of aerobic respiration. Therefore stem cells tend to havean overall anaerobic metabolism characterized by low mitochondrial activity and high expression of glycolytic enzymes. Alopecia areata (AA)The mechanism of action of PBM has some differences with that outlined above for AGA. Because AA is an autoimmune disease, the principle molecular signatures are characteristic of a pro-inflammatory nvironment in the HF. PBM has long been known to have a pronounced anti-inflammatory effect, but it is only recently that the possible mechanism for this has become apparent. Cells in the macrophage lineage can assume a diversity of phenotypes, and retain the capability to shift their function to maintain tissue homeostasis. Chemotherapy-induced alopecia (CIA) The mechanism of PBM is likely to operate via a different set of signaling pathways. It has long been known that PBM is able to protect cells at risk of dying. Many in vitro models have been utilized to show that PBM can inhibit apoptosis in different cells triggered by a number of different toxic substances. Thiseffect occurs due to the up-regulation of anti-apoptotic proteins, possible in the mitochondria. Another group of chromophores was identified in the HF, namely opsins. Opsins are blue-light responsivesignaling molecules, that were responsible for reducing apoptosis and prolonging the anagen phase in ex vivo HF that were treated with 3.2 J/cm2 of 453 nm LED light.Items Available: 1
1y
1
R 5,999
NEGOTIABLE
Price is per station, including char. Can be purchase as a single unit.Transform your salon with our deluxe hair station featuring an expansive 800x1500mm mirror paired with a comfortable chair. Elevate your clients' experience and streamline your workflow with this sleek and spacious setup, designed to enhance both style and functionality.
1d
7
R 2,000
NEGOTIABLE
Polo Tote bag Brown in colour Leather New and in Good Condition
4d
VERIFIED
6
R 80
NEGOTIABLE
Nordic style hair pin. Gorgeous mystical moth design in a beautiful rustic gold. + and extra hair pin for free.
Last image is just an example of how it can be worn, it's a really beautiful hair pin.
9d
VERIFIED
3
R 150
The curler is brand New inside box.
15d
1
Negotiable
NEGOTIABLE
We do all hair styles for cheap price
1mo
1
R 499
NEGOTIABLE
Professional Painless Eyebrow & Facial Hair Trimmer for Men and Women, Battery-Operated Trimmer with IPX7 Waterproof, Dual Edge Blades for Easy Cleansing Black.
2mo
VERIFIED
4
R 55
NEGOTIABLE
Cute and stylish boho hair scarf. A unique accessory to have, lifts up any outfit. Many ways to wear, last image shows a few. But you can get creative and wear is anyway you want
It can even be a belt over a shirt or dress. Or a mini scarf around your neck. Get creative with this versatile item.
Length 130cm
Width 6cm
2mo
VERIFIED
3
R 55
NEGOTIABLE
Cute and stylish boho hair scarf. A unique accessory to have, lifts up any outfit. Many ways to wear, last image shows a few. But you can get creative and wear is anyway you want
It can even be a belt over a shirt or dress. Or a mini scarf around your neck. Get creative with this versatile item.
Length 130cm
Width 6cm
2mo
VERIFIED
12
Negotiable
NEGOTIABLE
Glueless wigs available from 1350 depending with the length # frontal,# Installation
3mo
3
R 250
NEGOTIABLE
Ceramic hair straightener
Comes with instructions
Max 180 degrees , no heat loss, swivel cord
6mo
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