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Photobiomodulation (PBM) for Alopecia Androgenetic alopecia (AGA) The results of PBM for AGA suggest that the fraction of all the hair follicle (HF) in the anagen phase isincreased. This may be due to the ability of PBM to stimulate the mitochondria in the bulge stem cells. Stem cells are quiescent cells that have adapted to survive in their hypoxic niche. One of the mostdamaging agents to the longevity of cells is oxidative damage to DNA and other biomolecules, caused by the ROS that are an inevitable by-product of aerobic respiration. Therefore stem cells tend to havean overall anaerobic metabolism characterized by low mitochondrial activity and high expression of glycolytic enzymes. Alopecia areata (AA)The mechanism of action of PBM has some differences with that outlined above for AGA. Because AA is an autoimmune disease, the principle molecular signatures are characteristic of a pro-inflammatory nvironment in the HF. PBM has long been known to have a pronounced anti-inflammatory effect, but it is only recently that the possible mechanism for this has become apparent. Cells in the macrophage lineage can assume a diversity of phenotypes, and retain the capability to shift their function to maintain tissue homeostasis. Chemotherapy-induced alopecia (CIA) The mechanism of PBM is likely to operate via a different set of signaling pathways. It has long been known that PBM is able to protect cells at risk of dying. Many in vitro models have been utilized to show that PBM can inhibit apoptosis in different cells triggered by a number of different toxic substances. Thiseffect occurs due to the up-regulation of anti-apoptotic proteins, possible in the mitochondria. Another group of chromophores was identified in the HF, namely opsins. Opsins are blue-light responsivesignaling molecules, that were responsible for reducing apoptosis and prolonging the anagen phase in ex vivo HF that were treated with 3.2 J/cm2 of 453 nm LED light.Items Available: 1
1y
12
R 70
NEGOTIABLE
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COLOUR CHANGING SCHOE LACES Why you should have them?1. The white shoe laces changes to a green colour when in the shade after exposure in the sun.2. The glowing shoe laces makes it EASY to notice your shoes in the dark.Get Yours Now, available in Pretoria Central & BritsWhatsapp Kay: 067 739 9902 to see a video of the glowing shoe lace/view on YouTube Video 1: https://youtube.com/shorts/djv8ZH2n7Yk?si=O1tEyo7cuyFRpMUsVideo 2: https://youtube.com/shorts/PMT5blwhTDw?si=EZliVxIlVmN6pdra
1d
8
R 3,000
NEGOTIABLE
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Bernina Funlook 004D overlocker in very good condition.Perfect working condition
2d
5
R 1,500
NEGOTIABLE
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Selling size 9 shoes for men. Adidas pair and Soviet pair
3d
13
R 10,297
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Vaginal TighteningVaginal tissue, such as skin, can experience laxity as women age or go through childbirth. Microcirculation and blood flow in vaginal and urethral tissues decrease with menopause, and the decline in estrogen negatively impacting vaginal hydration and bladder function. The current rationale for treating the vaginal tissue with photobiomodulation is to stimulate synthesis of collagen and elastin in the vaginal tissue and supporting urethrovaginal sphincter and urethra, as well as promoting vasodilation in the vaginal and urethral submucosa.Birth Canal RehabilitationChildbirth is a transformative event in a woman’s life. The onset of motherhood presents a unique set of physical, emotional and psychological challenges. The post-partum phase can become even more challenging when the new mother experiences perineal or genital tract trauma as a result of childbirth. Gynecological pain imposes physical limitations on the new mother, making child-care, sitting, walking and other activities of daily living (ADLs) extremely difficult and painful. ?Perineal tears as a result of childbirth trauma are common with spontaneous vaginal birth. Research has shown that as many as 85% of all women will experience some kind of perineal tearing during childbirth. Lacerations of the perineum are defined and graded according to the structures that have been torn or injured.Photobiomodulation represents a safe alternative in the healing, rehabilitation and management of these conditions.Complete Treatment of the VulvaPhotobiomodulation can target deeper pelvic tissues such as the pelvic floor muscles and the bladder. For these reasons, photobiomodulation is now being used in patients with pelvic pain conditions.Eliminate Harmful BacteriaVulvovaginal candidiasis (VVC) and Bacterial Vaginosis (BV) are common infections of the female genitourinary tract. It is considered the two most common genital infection in women.From a 2019 study: given that the blue light-emitting diode (LED) is an electromagnetic radiation source with antimicrobial properties, the vulva and vagina were exposed to blue LED irradiation in a single session, divided into two applications. A reassessment was performed 21 days after the treatment. The light-emitting device had a visible spectrum, in the violet and blue ranges, and a maximum temperature increase of 7 °C. During the reassessment, the culture was found to be negative for fungus, and the signs and symptoms of the patient had disappeared.Vaginal RejuvenationFrom a resent study: HISTOLOGICAL OUTCOMES IN THE TREATMENT OF VULVOVAGINAL ATROPHY USING HOTOBIOMODULATION (PBM) TECHNOLOGYThe use of PBM in treating postmenopausal women suffering from symptoms of VVA showed improvement in both objective and subjective symptoms. The subjective improvements correlated to the related histological changes, showing an improvement in vaginal atrophy.Specifically, the histological samples three months post-treatment showed angiogenesis, increased vascularization in the lamina propria, neocollagenesis, increased thickness of the epithelium, and an increase the cellularity in the ECM, with no thermal damage effects.Finally, it is interesting to emphasize that the histological changes were maintained at 12 weeks, which suggests that if these patients continued the treatments at home, they could further improve or maintain the clinical benefits beyond the initial treatment protocol.Detoxing / Eliminating OdoursThe smell of your vagina may vary during your menstrual cycle, pregnancy, or menopause. You may also experience stronger smells after sexual intercourse or exercise.An intense odour, however, could be due to an infection that needs treatment. Bacterial vaginosis (BV) is a common cause of such odours.Reducing Vaginal DrynessSeveral studies reported effectively treat vaginal symptoms associated with GSM, such as vaginal dryness.Discover the Sana Domina at https://lightcare.co.za/sana-domina/Contact Light Care at Mail@lightcare.co.za012 743 6444 063 409 8742Items Available: 6
1y
R 6,500
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Try our LAYBUY option.
R1500 deposit to start laybuy, not less than R1000 installments as you are able, 6 month max for outstanding R3000. Once FULL AMOUNT of R6500 is PAID:
Two days of intense training as to tattoo depth, angle, speed, theoretical and practical, the law, medical, bloodbourne, airbourne, etc..
Registration by SAITA (The South African Institute of Tattoo Artists) and an International Certificate with your own unique registration number on.
3d
1
R 10,000
NEGOTIABLE
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2011 bottle of YSL La Nuit De L'Homme. Discontinued and very rare version of La Nuit De L'Homme. There is around 55ml left and comes with its box.
3d
1
R 12,000
NEGOTIABLE
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Dior Eau Noire 250ml. Discontinued and rare version of Dior Eau Noire. There is around 230ml left and comes with its box.
3d
2
R 1,000
NEGOTIABLE
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Small professional face steamer
5d
12
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I have this in stock for men all sizes.
100 % Quality at reasonable price.
Im based in Pretoria. we deliver around and nationwide..
6d
VERIFIED
12
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I have this in stock for men.. From medium sizes to 4XL
100% Quality at a reasonable price
Contact me im based in Pretoria we deliver around and courier nationwide.
6d
VERIFIED
6
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Soft warm blankets and we make sweater as well, any design any colours
6d
1
R 600
NEGOTIABLE
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Original Full black Converse All Star
6d
11
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Im selling quality sneakers for men. From size 3 to 12..contact me for price im based in Pretoria. We deliver and courier too
8d
VERIFIED
12
R 1,500
NEGOTIABLE
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Im selling men jeans including waxed ones.. 100% quality.
All sizes are available
Im based in Pretoria we do deliver around Gauteng and courier too. Contact me if interested.
8d
VERIFIED
12
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I sell quality stylish shoes from size 3 to 12..We deliver around Gauteng.. And courier too..Contact me for size and price the one you need. No time for chance takers this is not a scam
8d
VERIFIED
3
R 1,300
NEGOTIABLE
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De grendel sir david graaff first baronet of cape town for sale goes for r1700 willing to sell for r1300, bottle and case in perfect condtion bottle no 1143 of 4650
9d
1
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Are you looking to enter the
cosmetics industry and start your own business? Look no further than
Alora Cosmetics, your trusted partner in providing a turnkey solution.
With our expertise and high-quality products, you can easily kick start
your cosmetics venture and achieve success.One
of the key advantages of choosing Alora Cosmetics is our ability to
offer customizable labeling options. We understand the importance of
branding and how it can make your products stand out in a competitive
market. That's why we provide assistance in designing labels that align
with your vision and brand identity. Whether you already have a label
design in mind or need help creating one from scratch, our team of
experts is here to support you every step of the way.Additionally,
if you prefer not to start your own brand, we offer the opportunity to
sell our in-house brand. This option allows you to generate extra income
without the need to invest in branding and product development. Our
in-house brand is trusted by customers worldwide and offers a wide range
of hair care, perfumes and skincare products that deliver exceptional
results.WE DELIVER COUNTRY WIDE.FOR MORE INFORMATION WHATSAPP ONLY 0790580381EMAIL info@aloracosmetics.co.zaCheck Our Website www.aloracosmetics.co.za
9d
3
R 1,000
NEGOTIABLE
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Brand new various sizes and colour's.
42 ladies sized rings
35 Mens sized rings
Total of 77 silicone rings at a giveaway price, perfect for re-sell with plenty of margin to make, some shops sell one silicone ring for R 300, normal sales prices range from R100 per ring.
10d
1
R 3,250
NEGOTIABLE
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Prada Luna Rossa Extreme EDP 100ml. Discontinued and rare fragrance. There is around 40ml left and no box.
3d
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